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Ashwani Kumar Thakur

Ph.D. (I.M.T. & Panjab Univ.)

Professor, Department of Biological Sciences & Bioengineering (BSBE)

Research Interest



  • Ph.D., Institute of Microbial
    Technology & Panjab Univ., 2002
  • B.Sc., Himachal Pradesh Univ., 1993
  • M.Sc., Panjab Univ., 1995



  • Singh V, Rai RK, Arora A, Sinha N and Thakur AK (2014) Therapeutic implication of L-phenylalanine aggregation mechanism and its modulation by D-phenylalanine in phenylketonuria. Scientific Reports; 4:3875.
  • Thakur AK, Jayaraman M, Mishra R, Thakur M, Chellgran VM, Byon IJ, Conway JF, Gronenborn AM and Wetzel R (2009), Polyglutamine disruption of the huntingtin exon 1 N-terminus triggers a complex aggregation mechanism. Nature Structural & Molecular Biology; 16(4), 380-9.
  • Thakur AK, Yang W, Wetzel R (2004) Inhibition of polyglutamine aggregate toxicity by a structure-based elongation inhibitor. FASEB J; 18(7):923-925
  • Thakur AK, Wetzel R. (2002) Mutational analysis of the structural organization of polyglutamine aggregrates. Prot Natl Acad Sci (USA); 99(26):17014-17019
  • Thakur AK, Kishore R (1999) Novel hydrogen bonding ring motifs in a model peptide: crystal and molecular conformation. Chemical Communications; 1643-1644.

  • Alexander von Humboldt Fellow, Germany.


Department of BSBE
IIT Kanpur,
Kanpur 208016

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