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Course Contents

Types I Classes of Materials used in medicine: Polymers, Metals, Ceramics, Natural Materials and Composites. Degradable polymers and their use in medicine: Polymers, Hydro gels, Silicone biomaterials and medical fibers. Degradation of materials in the biological environment. Types of polymer degradation. Influence of polymer properties on degradation. Influence of biological environment on polymer degradation. Biological testing of biomaterials: In vitro assessment of materials for tissue compatibility. In vivo assessment of tissue compatibility. Host reactions to biomaterials and their evaluations: The role of adsorbed proteins in tissue response to biomaterials. Cell, extra cellular matrix, and tissue interactions with biomaterials. Inflammation, wound healing and foreign body response to biomaterials. Immune response to foreign materials. Toxicity, tumor genesis and biomaterials. Specific examples of applications of biomaterials in medicine.



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