Jayandharan Giridhara Rao

PhD (Christian Medical College, Vellore)

Professor, Department of Biological Sciences & Bioengineering (BSBE)


Research Interest



  • Post-doctoral Fellow- 2007-2009, Powell Gene Therapy Center, University of Florida, Gainesville, USA.
  • PhD [Biomedical sciences/ Molecular Biology]-2008, Christian Medical College, Vellore, India.



  • Microbiology and Immunology

  • Cellular & Molecular Biology

  • Biochemistry and Biochemical Engineering

Publications in 2019

  • Mary B, Maurya S, Kumar M, Bammidi S, Kumar V, Jayandharan GR*. Molecular engineering of Adeno-associated virus capsid improves its therapeutic gene transfer in murine models of hemophilia and retinal degeneration. Molecular Pharmaceutics 2019, 16:4738-4750.

  • Maurya S, Mary B, Jayandharan GR*. Rational engineering and evaluation of Neddylation and SUMOylation site modified AAV vectors in murine models of hemophilia B and Leber congenital amarousis. Hum Gene Ther 2019, doi:10.1089/hum.2019.164

  • Khan N, Bammidi, S, Jayandharan, GR*. A CD33 antigen targeted AAV6 vector expressing an inducible caspase-9 suicide gene is therapeutic in a xenotransplantation model of acute myeloid leukemia. Bioconjugate Chem. 2019, 30:2404-2416.

  • Mary B, Maurya S, Arumugam S, Kumar V, Jayandharan GR. Post-translational modifications in capsid proteins of recombinant adeno-associated virus (AAV) 1-rh10 serotypes. FEBS J. 2019, 286:4964-4981.

  • Dec 2019- Present Professor, Department of Biological Sciences and Bioengineering, IIT-Kanpur

  • Oct 2014- Dec 2019 Associate Professor, Department of Biological Sciences and Bioengineering, IIT-Kanpur


  • 2017-22 Senior Fellowship, Wellcome Trust DBT India Alliance

  • 2015 B.M. Birla Science Prize in Biology

  • 2014 Young scientist award, YIM-MIT Boston, USA

  • 2014-17 Senior Innovative Young Biotechnologist award, Department of Biotechnology, Government of India

  • 2012-17 Swarnajayanti Fellowship, Department of Science and Technology, Government of India

  • 2010-12 Bayer Hemophilia Early Career Investigator Award, Bayer Inc, USA


Department of Biological Sciences and Bioengineering
Indian Institute of Technology
Kanpur 208 016 (U.P)

Office Phone: 0512-259-4086
Fax Phone: 0512-259-4010

Email: jayrao[AT]iitk.ac.in

Gene Therapy, Molecular Genetics

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