Sanjeev Garg

Professor

  • Email

    sgarg[AT]iitk.ac.in

  • Office Phone No.

    +91-512-259-7736 (Office)
    +91-512-259-7860 (Lab)

  • Office & Lab

    Faculty Building 453 (Office)
    NL-II-301 (Lab)

  • Group Home Page IRINS Profile

Research Interest

  • Bioinformatics
  • Bioremediation
  • RNA interference
  • Computer aided product and process design
  • Flexibility analysis of chemical and biological systems

Education

  • B. Tech., HBTI, Kanpur, 1995
  • M. Tech., IIT Kanpur, 1997
  • Ph.D., University of Connecticut, Storrs, 2002
  • Post-doc, University of Nebraska-Lincoln, 2006

Research Overview

Activities in my research group focus on chemical and biological systems. This entails carrying out experiments in the laboratory, developing mathematical models and solving the models in single or multiple objective optimization frameworks. Experiments for elucidating the genetic aspects in azo dye degradation and mineralization of aromatic amines using novel bacterial consortium that will ultimately lead to novel remediation process; use of evolutionary (e.g., GA) and global optimization (e.g., BB, OA) techniques in graph-theoretic framework for array informatics (gene expression profiling and gene network analysis from cDNA microarray data); RNA interference using siRNA for neurodegenerative diseases; rational drug design (reverse engineering the structures of lead candidates from quantitative structure activity relationships) and reverse engineering the suitable biodegradable and biocompatible polymers for local and controlled drug delivery are some of the current research activities going on in the group.

Publications

  • Abdul Majid, Sanjeev Garg, Reactive oxygen species may cause amyloid beta aggregation by free radical polymerization, Journal of Applied Polymer Science, 141, 14 (2024).
  • C J Ramanan, S Garg, B J Bora, A Buradi, S Roy, P Sharma, N Alom, Influence of pressure in RO filtration of crude biodiesel, IOP Conf. Ser.: Earth Environ. Sci., 1074 (2024).
  • S. Dixit, S. Garg, Enzymatic degradation of sulphonated azo dye using purified azoreductase from facultative Klebsiella pneumoniae, Folia Microbiologica, 66, 79 (2020).
  • A. Pramanik, S. Garg, Design of diffusion-controlled drug delivery devices for controlled release of Paclitaxel, Chemical Biology & Drug Design, 94, 1478 (2019).
  • P. Chaudhari, S. Garg, Multi-Objective Optimization of Maleic Anhydride Circulating Fluidized Bed (CFB) Reactors, Chemical Engineering Research and Design, 141, 115 (2019).
  • S. Dixit and S. Garg, Biodegradation of environmentally hazardous azo dyes and aromatic amines using Klebsiella pneumoniae, Journal of Environmental Engineering, 144 (2018).
  • A. Chaudhary and S. Garg, siRNA Delivery using Polyelectrolyte-Gold Nanoassemblies in Neuronal Cells for BACE1 Gene Silencing, Material Science and Engineering:C, 80, 18 (2017).