Course contents:

1. Experimental Techniques

(A) Purification of Organic Compounds

• Recrystallisation

• Sublimation at atmospheric pressure and under reduced pressure

• Separation or organic compounds by Steam distillation

• Distillation of organic compounds under reduced pressure

• Bulb-to-bulb distillation under reduced pressure

(B) Chromatography

• Thin layer chromatography (TLC) and calculation of Rf values

• Column Chromatography: separation of organic mixture.

• Preparative TLC: preparation of plates and separation of organic mixtures

(C) Physical Constants

• Melting Points and Boiling Points

• Optical rotation and calculation of specific rotation and molecular rotation

(D) Spectroscopic Methods

• Preparation of an ester and its confirmation by IR and NMR

• Structure illucidation of unknown compounds based on the given spectral data

2. Investigation and Characterization of Organic Compounds

• Detection of elements present in a given organic compound.

• Identification of functional groups in a given organic compound.

• Identification of unknown organic compounds.

• Separation of organic mixture by chemical methods, preparation of derivatives, and identification of the material