Phase Transformable Cryogel Scaffold for Tissue Engineering

Patent Status: 

Patent Granted

Indian Patent Applicaton No: 

1775/DEL/2011

Grant: 

US8569062 B2

PCT filing No: 

PCT/IB2011/053522

International Patent No. Date: 

08.08.2011

Date Filed: 

23.06.2011

Date Granted: 

29.10.2013

Patent Category: 

Overview: 

Synthesis of biocompatible, biodegradable and phase transformable porous 3D cryogel scaffolds for tissue engineering.

Key Features: 

  • 3D Ciyogel scaffolds were prepared by cryogelation of stimuli-responsive terpolymers complexed with polyvinyl alcohol.
  • Biodegradability of the cryogel scaffold was designed to be dependent on the degradation of the polymeric matrix in presence of a monosaccharide.
  • Cryogelation process endows porosity to the phase transformable cryogels thus making them relevant materials for cell culture.

Applications: 

  • The phase transformable cryogels can be used to culture cells for use in a wide variety of applications, including, but not limited to, tissue repair or engineering.

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