A One-Pot Process For The Synthesis of Indole and Indole Derivatives

Patent Status: 

Patent Filed

Indian Patent Applicaton No: 

3880/DEL/2015

Department: 

Patent Category: 

Overview: 

 

Anone-pot process for the preparation of 2-alkyl indole

 

 

Key Features: 

  • Novel and improved process for the synthesis of indole derivatives such as 2-alkyl indole derivatives and halogenated 2-alkyl indole derivatives
  • N-activated aziridine derivative on reaction with heteroaromatic nucleophiles in the presence of a Lewis acid followed by metal catalysed C-N cyclization and aromatization leads to the preparation of indole derivatives in high purity and good yield.
  • The one pot process further helps in the reduction of overall time

Applications: 

  • Chemical industry

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