Development of an Extraction method for a Non-Ionic Surfactant Adsorbed on Biodegradable Polymeric Nanoparticles for Quantification

Patent Status: 

Patent Filed

Indian Patent Applicaton No: 

3003/DEL/2015

Patent Category: 

Overview: 

Novel solvent extraction process for removal of polysorbate 80 from nanoparticle surface

Key Features: 

  • Extracted moiety is polysorbate 80
  • Understanding mechanistic details of adsorption can be useful for studying nanoparticle interactions with key cellular players, for example, protein-nanoparticle interactions which ultimately decide their in vivo fate.

Applications: 

  • Drug delivery
  • Pharmacokinetics
  • Pharmacodynamics

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