Organic chemistry deals with the structure, properties, composition, reactions, and synthesis of carbon-containing compounds, called carbogens . The unique ability of the element carbon to form very stable covalent bonds with one another allows an infinite variety of architectural compositions, forms and sizes. The natural products are the naturally occurring organic compounds or carbogens which constitute the matter of all life (animals, plants) on earth. A study of these compounds at the molecular level provides an understanding of various phenomena in biological systems. Organic synthesis is the art of building organic molecules via chemical reactions. The synthesis of natural products is one of the most fascinating and challenging areas of research in chemistry. The chemical synthesis of these naturally occurring compounds as well as seemingly myriad of unnatural carbogens that could act as life saving drugs, useful materials, insecticides, etc. has contributed significantly to the present day comforts and continues to be at the core of chemical sciences contributing in a major way to other frontiers of science.
Our primary area of research centers on the design and synthesis of novel and structurally diverse molecular entities, which include (i) complex, multi-stereocentered natural products, (ii) aesthetically pleasing unnatural molecules and (iii) materials, viz molecular rods, chains and polyfunctional molecules, by utilizing the recently developed methodologies in our laboratory.
The rational design of strained polycylic heterocycles has been exhilarating and fascinating, nevertheless a difficult synthetic task to accomplish. Synthesis of target molecules with unusual geometries, marvelous structural architecture and exploration of their physicochemical properties has been one of the challenging research activities of contemporary chemists. In this context, we have designed and accomplished the synthesis of novel oxa-bridged compounds. These rigid molecular frameworks could act as polyfunctional scaffolds upon suitable elaboration.
For more details of the above study, please contact:
Professor F. A. Khan
Department of Chemistry
Indian Institute of Technology Kanpur