The center involves active researchers in the area of Biomaterials. As part of this center, the leading researchers from two academic institutions and two R & D labs will participate from Indian side. From USA side, researchers from three reputed academic institutes and one private industry will participate. In addition, one US based private industry, one Indian private industry and one Indian R & D institute provide full support to the proposed center. The overall objective of the proposed center is to combine the cutting edge technologies of fabrication and testing of materials science with the knowledge of biological sciences in order to come up with strategies to develop shaped implant materials in some of the emerging material systems for the purpose of the enhancement of public health. The proposed center will attempt to demonstrate the synergistic flow and utilization of scientific concepts, technological ideas and expertise in an international team of recognized scientists. Each of the team members is capable of executing cutting edge research in their own field, however, to bring such an interdisciplinary research project to fruition we need to utilize and merge the capabilities of each group to the fullest. The focused activities for the center would be in the following areas: (a) Metals, ceramics and polymer based hard tissue replacement (orthopedic implant) materials, with particular emphasis on Nanobiomaterials; (b) Polymer based scaffold materials for tissue engineering application and (c) Formulating strategies based on novel manufacturing routes to Produce complex shaped implant materials