Microanalysis is the most important chemical analysis that is required for organic, inorganic and organometallic compounds. This is a basic and important facility that gives valuable primary information of the composition of a chemical compound, i.e., various elements present in the compounds. Using this method, normally the percentage of elements, such as C, H, N, S / O present in the organic compounds can be obtained experimentally. This technique is based on the combustion process where the sample (~1-2 mg) is heated to high temperature in the presence of oxygen atmosphere. The oxidized and the reduced volatiles, such as CO2, H2O and N2, have been absorbed using different traps separately and the quantity of the gases absorbed is measured using the detectors (Charts 1 and 2). From this the values of the C, H, and N present in the organic compounds can be found. Although this method has been known widely for the organic compounds, nowadays, metal-organic, organometallic, and the coordination compounds have also been used for the measurements of the C, H, and N elemental composition.