Department of Chemical Engineering, IIT Kanpur

Raghvendra Singh
Assistant Professor


Education:

Ph.D., State University of New York at Buffalo, 2008

B.E., University of Roorkee, 1998

Phone: 91-512-2597605 (office)

email: raghvend@iitk.ac.in

 

Research Interests

  • Molecular dynamics of biological molecules

 

Brief Overview

 

Our major research interest is molecular dynamics. Here, we attempt to understand complex biological phenomena from first principles then apply mathematical analysis to gain insight into how different components of biological systems interact. From analysis and mathematical modeling, we answer questions that may be significant for experimentalists.

 

Selected Publications

  •  Singh R. (2016) "Central role of PI3K–SYK interaction in fibrinogen-induced lamellipodia and filopodia formation in platelets", FEBS Open Bio DOI:10.1002/2211-5463.12149.

  •  Singh R (2016) "Model Predicts That MKP1 and TAB1 Regulate p38α Nuclear Pulse and Its Basal Activity Through Positive and Negative Feedback Loops in Repsonse to IL-1", PLoS ONE doi:10.1371/journal.pone.0157572".

  •  Singh R (2013) "Signal Oscillation Is Another Reason for Variability in Microarray-Based Gene Expression Quantification", PLoS ONE 8(1): e54753. doi:10.1371/journal.pone.0054753".

  •  Gupta S, Singh R (2012) "Analysis of the Virus Dynamics Model Reveals That Early Treatment of HCV Infection May Lead to the Sustained Virological Response", PLoS ONE 7(7): e41209. doi:10.1371/journal.pone.0041209.

  •  Singh, R., Nitsche, J.M. and Andreadis, S.T. (2009) “An Integrated Reaction-Transport Model for DNA Surface Hybridization: Implications for DNA Micro arrays”, Annals of Biomedical Engineering, 2009 Jan;37(1):255-69.

  • Singh, R., Lei, P., and Andreadis, S. T. (2009). “PKC-delta binds to E-cadherin and mediates EGF induced cell-scattering”, Experimental cell research,July, 2009; doi:10.1016/j.yexcr.2009.07.002.

  • Singh, R. and Andreadis, S. T. (2007). “EGF receptor activation decreases retroviral gene transfer through protein kinase C-delta.” Molecular Therapy 2007 Feb; 15(2):369-77.